Foreword by Martin Leon
1. Epidemiology and Historical Perspectives
Peter Clemmensen, Kari Saunamäki
2. Pre-hospital Diagnosis and Management of Acute Myocardial Infarction
Gilles Montalescot, Patrick Goldstein
3. Presentation of AMI – Symptoms, Examination, Biomarkers and Atypical Presentations
Christopher P. Moriates, Kabir J. Singh, Alan S. Maisel
4. The Definition of Myocardial Infarction
Kristian Thygesen, Joseph S. Alpert, and Allan S. Jaffe
5. Optimal Reperfusion Therapy: Clinical trial evidence of primary angioplasty and (prehospital) fibrinolysis
Freek W.A. Verheugt
6. Adjunctive Pharmacologic Therapies
Gregory Ducrocq, Philippe Gabriel Steg
7. Primary Percutaneous Coronary Intervention: Role of Stenting versus Balloon Angioplasty and Drug-Eluting Stents versus Bare Metal Stents. Trial Evidence and Current Concepts
Robert A. Byrne, Adnan Kastrati
8. Primary Percutaneous Coronary Intervention: Culprit-Lesion Only versus Multivessel Intervention
Thomas Pilgrim, Stephan Windecker
9. Management of Mechanical Complications of Myocardial Infarction: Ventricular Septal Defect, Mitral Regurgitation, Free-Wall Rupture
Imran Saeed, Marjan Jahangiri
10. Primary Coronary Angioplasty: The Role of Mechanical Circulatory Support
Luiz Alberto Mattos, Pedro Beraldo de Andrade
11. Primary Angioplasty: Methods of Reducing Infarct Size and Reperfusion Injury
Michael Gick, Jan Minners, Franz-Josef Neumann
12. Primary Angioplasty: The Importance of Time to Reperfusion, Door to Balloon Times and How to Reduce Them
Atman P. Shah, William J. French
13. Systems of Care for Primary Percutaneous Coronary Intervention
Abhiram Prasad
14. Utilization of Facilitated and Rescue Angioplasty
Rajiv Gulati, Bernard J. Gersh
15. Opportunities and Challenges of Stem Cell Therapy: Is there a role in AMI
Barry H. Trachtenberg, Joshua M. Hare
16. (A) Primary Angioplasty in Health Care Delivery: The North American Model
Jacob Thorsted Sorensen, Christian Juhl Terkelsen, Steen Dalby Kristensen
16. (B) Primary Angioplasty in Healthcare Delivery: The North American Model
Faisal Latif, Kintur Sanghvia, Cindy L. Grines MD
17. Special Management of the Diabetic Patients with STEMI
Salvatore Brugaletta, Manel Sabaté
18. Role of Surgery in Acute Myocardial Infarction
Yasir Abu-Omar, David P. Taggart
1. Epidemiology and Historical Perspectives
Peter Clemmensen, Kari Saunamäki
2. Pre-hospital Diagnosis and Management of Acute Myocardial Infarction
Gilles Montalescot, Patrick Goldstein
3. Presentation of AMI – Symptoms, Examination, Biomarkers and Atypical Presentations
Christopher P. Moriates, Kabir J. Singh, Alan S. Maisel
4. The Definition of Myocardial Infarction
Kristian Thygesen, Joseph S. Alpert, and Allan S. Jaffe
5. Optimal Reperfusion Therapy: Clinical trial evidence of primary angioplasty and (prehospital) fibrinolysis
Freek W.A. Verheugt
6. Adjunctive Pharmacologic Therapies
Gregory Ducrocq, Philippe Gabriel Steg
7. Primary Percutaneous Coronary Intervention: Role of Stenting versus Balloon Angioplasty and Drug-Eluting Stents versus Bare Metal Stents. Trial Evidence and Current Concepts
Robert A. Byrne, Adnan Kastrati
8. Primary Percutaneous Coronary Intervention: Culprit-Lesion Only versus Multivessel Intervention
Thomas Pilgrim, Stephan Windecker
9. Management of Mechanical Complications of Myocardial Infarction: Ventricular Septal Defect, Mitral Regurgitation, Free-Wall Rupture
Imran Saeed, Marjan Jahangiri
10. Primary Coronary Angioplasty: The Role of Mechanical Circulatory Support
Luiz Alberto Mattos, Pedro Beraldo de Andrade
11. Primary Angioplasty: Methods of Reducing Infarct Size and Reperfusion Injury
Michael Gick, Jan Minners, Franz-Josef Neumann
12. Primary Angioplasty: The Importance of Time to Reperfusion, Door to Balloon Times and How to Reduce Them
Atman P. Shah, William J. French
13. Systems of Care for Primary Percutaneous Coronary Intervention
Abhiram Prasad
14. Utilization of Facilitated and Rescue Angioplasty
Rajiv Gulati, Bernard J. Gersh
15. Opportunities and Challenges of Stem Cell Therapy: Is there a role in AMI
Barry H. Trachtenberg, Joshua M. Hare
16. (A) Primary Angioplasty in Health Care Delivery: The North American Model
Jacob Thorsted Sorensen, Christian Juhl Terkelsen, Steen Dalby Kristensen
16. (B) Primary Angioplasty in Healthcare Delivery: The North American Model
Faisal Latif, Kintur Sanghvia, Cindy L. Grines MD
17. Special Management of the Diabetic Patients with STEMI
Salvatore Brugaletta, Manel Sabaté
18. Role of Surgery in Acute Myocardial Infarction
Yasir Abu-Omar, David P. Taggart
Stephen Brecker, M.D
He is a Consultant Cardiologist at St. George’s Hospital, London, UK and is an Honorary Senior Lecturer at St. George’s University of London. He is the Care Group Lead for Cardiology and Director of Cardiac Catheterisation Laboratories at St. George’s Hospital in London. He received his medical degree from St. Thomas' Hospital Medical School, University of London. A highly experienced specialist in interventional cardiology, Dr. Brecker is a frequent speaker at national and international meetings. He is a fellow of the Royal College of Physicians, European Society of Cardiology, and American College of Cardiology. The author of over 70 scientific papers, Dr. Brecker is a frequent reviewer for many prestigious medical journals including Circulation, Journal of the American College of Cardiology, and Heart. His research interests include use of echocardiography to assess ventricular function, and the role and efficacy of transcatheter aortic valve implantation.
Martin Rothman, M.D., Consultant Cardiologist
He is the Director of Cardiac Research and Development at Barts and the London NHS Trust. Dr. Rothman received his medical degree from the University of Manchester Medical School and is an Honorary Professor of Interventional Cardiology at Queen Mary, University of London. A pioneering figure in the field of interventional cardiology, he helped to establish Europe’s largest heart attack center. He also co-founded the British Cardiovascular Intervention Society. Dr. Rothman, author of several books and numerous peer-reviewed journal articles, serves on the editorial board of several medical journals including the International Journal of Cardiovascular Intervention, Intravascular Imaging, and Catheterization and Cardiovascular Intervention. Dr. Rothman is committed to the innovation of new intravascular cardiovascular devices; he has been instrumental in the development and advancements of intravascular ultrasound and helped to develop a novel abdominal aortic aneurysm percutaneous device.
He is a Consultant Cardiologist at St. George’s Hospital, London, UK and is an Honorary Senior Lecturer at St. George’s University of London. He is the Care Group Lead for Cardiology and Director of Cardiac Catheterisation Laboratories at St. George’s Hospital in London. He received his medical degree from St. Thomas' Hospital Medical School, University of London. A highly experienced specialist in interventional cardiology, Dr. Brecker is a frequent speaker at national and international meetings. He is a fellow of the Royal College of Physicians, European Society of Cardiology, and American College of Cardiology. The author of over 70 scientific papers, Dr. Brecker is a frequent reviewer for many prestigious medical journals including Circulation, Journal of the American College of Cardiology, and Heart. His research interests include use of echocardiography to assess ventricular function, and the role and efficacy of transcatheter aortic valve implantation.
Martin Rothman, M.D., Consultant Cardiologist
He is the Director of Cardiac Research and Development at Barts and the London NHS Trust. Dr. Rothman received his medical degree from the University of Manchester Medical School and is an Honorary Professor of Interventional Cardiology at Queen Mary, University of London. A pioneering figure in the field of interventional cardiology, he helped to establish Europe’s largest heart attack center. He also co-founded the British Cardiovascular Intervention Society. Dr. Rothman, author of several books and numerous peer-reviewed journal articles, serves on the editorial board of several medical journals including the International Journal of Cardiovascular Intervention, Intravascular Imaging, and Catheterization and Cardiovascular Intervention. Dr. Rothman is committed to the innovation of new intravascular cardiovascular devices; he has been instrumental in the development and advancements of intravascular ultrasound and helped to develop a novel abdominal aortic aneurysm percutaneous device.
“Clinical Guide to Primary Angioplasty should be viewed as required reading for any health care professional involved with acute MI treatment.”
– From the foreword by Dr. Martin Leon, Chairman Emeritus, Cardiovascular Research Foundation
– From the foreword by Dr. Martin Leon, Chairman Emeritus, Cardiovascular Research Foundation

