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Human Developmental Toxicants: Aspects of Toxicology and Chemistry

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Human Developmental Toxicants: Aspects of Toxicology and Chemistry

By James L. Schardein, Leesburg, Florida, USA and Orest T. Macina, Cleveland, Ohio, USA

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$184.00
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Book Specifications

  • Available to Purchase
  • Published: August 2006
  • ISBN: 9780849372292
  • First Edition
  • 427 pages
  • Format: Hardcover
  • Size: 7" x 10"
  • 295 Black and White Illustrations

Quick Overview

Human Developmental Toxicants offers up-to-date and concise information on the chemical structures, properties and biological activities for 50 known agents that adversely affect prenatal and postnatal human development. Focusing on one compound per chapter, the book also includes associated biological data from animals for each agent.

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Human Developmental Toxicants offers up-to-date and concise information on the chemical structures, properties, and biological activities for 50 known agents that adversely affect prenatal and postnatal human development. Focusing on one compound per chapter, the book also includes associated biological data from animals for each agent. An accompanying CD summarizes all of the data discussed in the text within an electronic database. The CD also contains three-dimensional structure representations and 49 calculated physicochemical and topological parameters of each toxicant, useful for building structure activity relationship (SAR) models linking the chemical properties with observed human developmental toxicity.

Features:

  • discusses 50 known agents that adversely effect human development as a result of exposure
  • offers insight into identifying the chemical properties responsible for adverse effects on human development
  • focuses on the relationship between chemical characteristics and toxicological properties of important toxicants
  • contains pertinent animal data to compare and correlate with human data
  • supplies an accompanying CD-ROM with three-dimensional chemical structures, chemical properties and toxicological data in SD and Excel file form for each toxicant