Part I: Physiology of Oral Drug Absorption

• General Gastrointestinal Physiology relevant to drug absorption
• Absorption mechanisms in the GI tract
• Gastrointestinal Transit and Drug Absorption
• Gut Wall Metabolism
• Food effects on dosage form performance
• Diseases affecting drug absorption

Part II: The Biopharmaceutics Classification System

• The Biopharmaceutics Classification Scheme
• Solubility in the GI tract
• Permeability measurement
• In vivo biopharmaceutics: Experience from intestinal perfusion in humans
• Alternatives to BCS using First Pass metabolism in the gut and liver

Part III: Non-clinical methods to evaluate oral formulations

• Dissolution testing to forecast in vivo performance of IR formulations
• Dissolution testing to forecast in vivo performance of MR formulations
• Analysis of Drug Dissolution Data
• Formulation Screening in the Pharmaceutical Industry I
• Formulation Screening in the Pharmaceutical Industry II
• Animal models for screening oral formulations - an update
• Computer models for predicting drug absorption

Part IV: Bioequivalence studies

• Bioavailability and Bioequivalence studies
• Biowaiving based on the BCS - A Global Comparison
• Biowaiving based on IVIVC
• Appendix: Excel sheet programme (as CD)

American Journal of Pharmaceutical Education (for the first edition)