• 1. Introduction
• 2. Impurities in Raw Water
• 3. Pretreatment Techniques
• 4A. Ion Removal Techniques - Reverse Osmosis
• 4B. Ion Removal Techniques - Ion Exchange
• 5. Distillation and Pure Stream Generation
• 6. Storage Systems and Accessories
• 7. Ozone Systems and Accessories
• 8. Polishing Components
• 9. Distribution Systems - Design, Installation, and Material Selection
• 10. Controls and Instrumentation
• 11. System Design and Specification Guidelines
• 12. System Installation, Start-Up, and Commissioning
• 13. System Validation

William V. Collentro, M.S. ChE has spent nearly 45 years of his career working in water purification and related areas. He received his Bachelor's of Science and Master's of Science degrees in chemical engineering from Worcester Polytechnic Institute (WPI). Currently, he is visiting assistant professor at WPI. He is also the founder and a senior consultant for Water Consulting Specialists, Inc. of Doylestown, PA which he established in 1993.

Mr Collentro's additional academic associations include adjunct professor at Stevens Institute of Technology and a faculty member at Parenteral Drug Association's Training and Research Institute (PDA-TRI). He has written more than 100 technical articles and is on the editorial board of Journal of Validation Technology and Journal of GXP Compliance. He has also performed consulting, engineering, design, validation and related activities for over 300 clients.

Mr. Collentro is the inventor of two US patents for production of high purity water using reverse osmosis. In 1998 he received the PDA-TRI James P. Agalloco Award for excellence in teaching. He is a member of several professional organizations including PDA, ISPE, ACS, AIChE, AWWA, AFS, and WQA.

"This is a comprehensive overview of the technical aspects of water purification systems, with discussions of compendial requirements and regulatory aspects.....The author seems to target the individuals involved with the design and development of pharmaceutical water systems, and this is an excellent reference for them. The author is known as an expert with many years of working experience in this area. This book provides a thorough discussion of the technical aspects related to water purification systems.......Theories and principles involved in production of different types of USP/EP waters are presented with great deal of technical expertise. System specification, maintenance, and validation are well covered.......The author's extensive work experience in this field is reflected throughout the book, which will serve as an excellent reference for anyone involved in manufacturing pharmaceutical waters"

Doody's Notes

[REVIEWER'S EXPERT OPINION]

Rahmat M Talukder, Ph.D.(Southwestern Oklahoma State University College of Pharmacy)