- Contents
- Introduction
- Claude Lenfant Preface
- Contributors
Section 1: Classification, Epidemiology, Pathology, Pathogenesis and Genetics
- Updated Clinical Classification of Pulmonary Hypertension Ivan M. Robbins and Ge´rald Simonneau
- Epidemiology of Pulmonary Arterial Hypertension Marc Humbert
- Pathology of Pulmonary Hypertension Peter Dorfmu¨ ller
- Pathogenesis of Pulmonary Hypertension Norbert F. Voelkel, Lori Sweeney, and Herman Bogaard
- Animal Models of Pulmonary Hypertension Laurence Dewachter and Robert Naeije
- Genetics of PAH Eric D. Austin, James E. Loyd, and John A. Phillips III
Section 2: Imaging and Diagnosis of Pulmonary Hypertension
- Imaging of Pulmonary Hypertension Dominique Musset and Sophie Maıˆtre
- Echocardiography of Pulmonary Arterial Hypertension
- Diagnosis and Hemodynamic Assessment of Pulmonary Arterial Hypertension Rajan Saggar, Rajeev Saggar, John A. Belperio, David A. Zisman, Joseph P. Lynch III, and Jamil Aboulhosn
Section 3: Clinical Variants of Pulmonary Hypertension
- Idiopathic, Familial, and Anorexigen-Associated Pulmonary Arterial Hypertension Jerome Le Pavec and Marc Humbert
- Pulmonary Arterial Hypertension Complicating Connective Tissue Diseases Paul M. Hassoun
- Pulmonary Arterial Hypertension in Congenital Heart Disease Daniel S. Levi, Victoria Scott, and Jamil Aboulhosn
- Pulmonary Arterial Hypertension and Human Immunodeficiency Virus Infection Bruno Degano and Olivier Sitbon
- Portopulmonary Hypertension Michael J. Krowka
- Pulmonary Hypertension Complicating Schistosomiasis Caio J. C. S. Fernandes, Carlos Jardim, and Roge´rio Souza
- Pulmonary Hypertension in Sickle Cell Disease Mark T. Gladwin
- Pulmonary Veno-occlusive Disease and Pulmonary Capillary Hemangiomatosis David Montani
- Pulmonary Hypertension in Chronic Obstructive Pulmonary Disease Emmanuel Weitzenblum and Ari Chaouat
- Pulmonary Hypertension Complicating Interstitial Lung Disease David A. Zisman, John A. Belperio, Rajan Saggar, Rajeev Saggar, Michael C. Fishbein, and Joseph P. Lynch III
- Pulmonary Hypertension in Chronic Mountain Sickness Dante Penaloza and Francisco Sime
- Chronic Thromboembolic Pulmonary Hypertension William R. Auger and Peter F. Fedullo
Section 4: Medical Treatment of Pulmonary Arterial Hypertension
- Pulmonary Arterial Hypertension: Conventional Therapy Olivier Sitbon
- Medical Treatment of PAH: Prostacyclins Paul R. Forfia and Vallerie V. McLaughlin
- Phosphodiesterase Type 5 Inhibitors Nazzareno Galie`
- Medical Treatment of Pulmonary Arterial Hypertension: Endothelin Receptor Antagonists Kristina Kemp and Marc Humbert
- Medical Treatment of PAH: Combination Therapy, Novel Agents, Future Directions, and Current Recommendations Lewis J. Rubin and Sean P. Gaine
- Goal-Oriented Therapy in Pulmonary Arterial Hypertension Marius M. Hoeper
Section 5: Atrioseptostomy and Surgery for Pulmonary Hypertension
- Atrial Septostomy for the Treatment of Severe Pulmonary Hypertension Julio Sandoval, Jorge Gaspar, and Toma´s Pulido
- Surgical Management of Pulmonary Hypertension Philippe G. Dartevelle, Elie Fadel, Sacha Mussot, Dominique Fabre, Olaf Mercier, Marc Humbert, and Ge´rald Simonneau
- The Selection and Timing of Transplantation for Patients with Pulmonary Arterial Hypertension Paul A. Corris
Section 6: Difficult Pulmonary Hypertension
- Pulmonary Arterial Hypertension and Pregnancy Xavier Jai¨s, Laura Claire Price, Florence Parent, and Marc Humbert
- Pediatric Pulmonary Hypertension Cecile Tissot and Maurice Beghetti
- Practical Management of Pulmonary Arterial Hypertension in the Intensive Care Unit Benjamin Sztrymf and Marc Humbert
Section 7: Endpoints and Clinical Trials
- End Points and Clinical Trial Design in Pulmonary Arterial Hypertension: Clinical and Regulatory Perspectives Andrew J. Peacock Index
- Marc Humbert, Universite Paris, Clamart, France
- Joseph P. Lynch, III UCLA, Los Angeles, California, USA
Professor of Respiratory Medicine, the South Paris University, Clamart, France
Professor of Clinical Medicine in the Division of Pulmonary and Critical Care Medicine, Clinical Immunology and Allergy, David Geffen School of Medicine at UCLA, Los Angeles, California, USA. Dr. Lynch received his M.D. from Harvard Medical School, Boston, Massachusetts, USA. He is a member and fellow of several professional organizations, including the American Thoracic Society and the American College of Chest Physicians. Dr. Lynch has been invited to speak at more than 400 seminars and lectures, and he currently serves as Editor-in-chief of the publication Seminars of Respiratory and Critical Care Medicine. Dr. Lynch is also on the editorial board of other publications, such as Clinical Pulmonary Medicine, Pulmonary Infections Forum, and Clinical Medicine: Respiratory and Pulmonary Medicine. From 1992–2008, he has been cited in The Best Doctors in America and from 2001–2007, he has been cited in America’s Top Doctors. Dr. Lynch is also the editor of Informa Healthcare’s Idiopathic Pulmonary Fibrosis and Lung and Heart-Lung Transplantation.
