• Anatomy/Biomechanics
• 1. Pathogenesis of Obstructive Sleep Apnea: Insights from Upper Airway Imaging Studies
• 2. Biomechanics of the Upper Airway during Sleep
• Neural Mechanisms
• 3. Sleep-Induced Breathing Instability
• 4. Mechanisms of Upper Airway Hypotonia
• 5. Autonomic Consequences of Arousal from Sleep and Neural Mechanisms of Arousal

• Studies in Humans
• 6. Airway Reflexes—Changes with Sleep
• 7. Gender Differences in Sleep-disordered Breathing

• Sleepiness
• 8. Mechanisms of Sleepiness in Obstructive Sleep Apnea
• 9. Neuroimaging Studies in Obstructive Sleep Apnea
• 10. Biomarkers and Obstructive Sleep Apnea
• Cardiovascular Consequences
• 11. Obstructive Sleep Apnea and Hypertension – Interactions and Clinical Implications
• 12. Other Cardiovascular Consequences of Sleep Apnea
• Endocrine
• 13. Neuroendocrine Aspects of Sleep Apnea
• 14. Obstructive Sleep Apnea and Glucose Metabolism
• Intermittent Hypoxia
• 15. Intermittent Hypoxia and Neurocognitive Function
• 16. Obstructive sleep apnea: Mechanisms of Intermittent Hypoxemia Neural Injury

• 17. Screening for Sleep Apnea
• 18. Alternative Strategies for Diagnosis of Patients with Obstructive Sleep Apnea

• 19. Obstructive Sleep Apnea: Children versus Adults
• 20. Sleep Apnea in Older Adults
• 21. Obstructive Sleep Apnea in Pregnancy and Menopause

• 22. Adherence to CPAP Treatment and Functional Status in Adult Obstructive Sleep Apnea
• 23. CPAP Therapy: Results of Randomized Controlled Trials in Obstructive Sleep Apnea
• 24. Oral Appliance Therapy for Snoring and Sleep Apnea
• 25. Upper Airway Surgery for Obstructive Sleep Apnea
• 26. Pharmacotherapeutic Trials for Sleep-Disordered Breathing

• 22. Adherence to CPAP Treatment and Functional Status in Adult Obstructive Sleep Apnea - Terri E. Weaver, Judith Reishtein and Amy Sawyer
• 23. CPAP Therapy: Results of Randomized Controlled Trials in Obstructive Sleep Apnea - Sophie D. West and John R. Stradling
• 24. Oral Appliance Therapy for Snoring and Sleep Apnea - Peter A. Cistulli and Ali M. Darendeliler
• 25. Upper Airway Surgery for Obstructive Sleep Apnea - Edward Weaver and Andrew N. Goldberg
• 26. Pharmacotherapeutic Trials for Sleep-Disordered Breathing - Jan Hedner and Ding Zou

Allan I. Pack, MBChB, PhD, is the Chief of the Division of Sleep Medicine and the Director of the Center for Sleep and Respiratory Neurobiology at the University of Pennsylvania. A Professor of Medicine, Dr. Pack received his training in Glasgow, Scotland. He is the recipient of the John L. Miclot endowed chair.
His research concerns the genetics/genomics of sleep and its disorders.
He is a member of the following organizations: American Association for the Advancement of Science, American Federation for Clinical Research, American Physiological Society, American Academy of Sleep Medicine, American Society for Clinical Investigation.