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Toxicology of the Nose and Upper Airways

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Toxicology of the Nose and Upper Airways

By John B. Morris, University of Connecticut, Stoors, Connecticut, USA
Dennis J. Shusterman, University of California, San Francisco, California, USA

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$173.00
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This publication is available in both printed and electronic format:

    

Book Specifications

  • Available to Purchase
  • Published: February 2010
  • ISBN: 9781420081879
  • eISBN: 9781420081886
  • First Edition
  • 450 pages
  • Format: Hardcover
  • Size: 6.125 x 9.25
  • 50 Black and White Illustrations

Quick Overview

An essential reference not only to pharmacologists and toxicologists, but also to clinicians, risk assessors, and sensory scientists concerned with the nose and upper airway.
$173.00
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Presenting cutting-edge information on both human and animal toxicology of the upper respiratory tract, Toxicology of the Nose and Upper Airways serves as an essential reference not only to pharmacologists and toxicologists, but also to clinicians, risk assessors, and sensory scientists concerned with the nose and upper airway.
This up-to-date and comprehensive review of nasal toxicology highlights recent developments in the recognition of the nose as a target of air pollutants, a route of entry for toxicants, and a possible route of administration for drugs into the central nervous system.

Key features in this state-of-the-art guide include:


  • Comparing and contrasting of mechanistic approaches to risk assessment for inhaled toxicants, including modern modeling concepts for rodent to human extrapolation
  • The nose as a potential model system for studying respiratory toxicology
  • Xenobiotic metabolism and signaling mechanisms in nasal toxicology
  • Considerations of the often unexplored topics of sensory endpoints and neurogenic mechanisms
  • Exploration of anatomy, dosimetry, mucosal enzymology, reflex responses to nasal irritation, and acute and chronic toxicity
  • Emphasis on parallel or integrated considerations of data deriving from experimental animal and human studies
  • A review of newer epidemiologic findings from populations exposed occupationally or environmentally